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| All Schools |
| All Sports |
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| Football | | 9.02.2022 – South Portland 35, Marshwood 26 |
| 9.10.2022 – South Portland 36, Gorham 14 |
| 9.16.2022 – Massabesic 14, South Portland 13 |
| 9.23.2022 – Cape Elizabeth 41, South Portland 13 |
| 9.30.2022 – South Portland 21, Noble 0 |
| 10.07.2022 – South Portland 28, Biddeford 0 |
| 10.15.2022 – South Portland 27, Scarborough 7 |
| 10.21.2022 – Portland 20, South Portland 13 |
| 10.28.2022 – South Portland 29, Marshwood 8 |
| 11.04.2022 – South Portland 22, Massabesic 6 |
| 11.11.2022 – Portland 29, South Portland 20 |
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